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"Creatinine"

Ameliorative effect of lycopene alone and in combination with co-enzyme Q10 in streptozotocin-induced diabetic nephropathy in experimental rats

Pooja B. Rasal, Gaurav N. Kasar, Manoj S. Mahajan, Aman B. Upaganlawar, Chandrashekhar D. Upasani

Diabetic nephropathy (DN) has become an utmost reason for long-standing renal dysfunction and end-stage renal disease globally. Oxidative stress induced by persistent…

#Antioxidants #CoQ10 #Diabetic nephropathy #Lycopene
p. 123-130
10.29228/ijpbp.24
DOI: https://doi.org/10.29228/ijpbp.24

Ameliorative effect of zingerone on cadmium-induced nephrotoxicity in adult wistar rats

Augustine Oviosun, Emeka Godson Anyanwu, Ezinne Chidinma Oviosun, Okwara Blasius Okechukwu

Exposure to heavy metals like cadmium has been reported to cause severe kidney damage through oxidative stress and inflammation. Zingerone is a bioactive compound…

#Zingerone #Oxidative stress #Renal toxicity #Cadmium
p. 118-124
10.62313/ijpbp.2024.238
DOI: https://doi.org/10.62313/ijpbp.2024.238

Therapeutic effect of the solvent fraction of hexane leaf extract of Tapinanthus bangwensis (Engl. & K. Krause) (Loranthaceae) in alloxan-induced pathology in diabetic rats

Godwin Okwudiri Ihegboro, Chimaobi James Ononamadu, Mujiburrahman Fadilu, Peter Prince Oghenekome, Bello Jacob, Sunday Edwin

Plant-based products are gradually replacing pharmaceuticals in treating ailments, including diabetes, due to their safety, cost-effectiveness, potency, and…

#Oxidative stress #Tapinanthus bangwensis #Diabetic rats #Haematopoietic markers
p. 79-89
10.62313/ijpbp.2024.196
DOI: https://doi.org/10.62313/ijpbp.2024.196

Toxicity study and ameliorative effects of the aqueous leaf extract of Lecanoidiscus cupanioides Planch (ex. Benth) on the stress-induced ulcer

Ebere Ifejirika Ezeonyi, Earnest Oghenesuvwe Erhirhie, Felix Ahamefule Onyegbule

Lecaniodiscus cupanioides Planch (ex. Benth) is effective in treating burns, fevers, and inflammatory conditions. This study investigates the toxicity effects of the…

#Lecaniodiscus cupanioides #Toxicity studies #Stress induced ulcer #Water immersion
p. 47-55
10.62313/ijpbp.2024.159
DOI: https://doi.org/10.62313/ijpbp.2024.159

Unveiling the antimalarial properties of Terminalia ivorensis (A. Chev) stem bark aqueous extract: In vivo efficacy testing and in silico predictions

Mariscal Brice Tchatat Tali, Eugenie Aimée Madiesse Kemgne, Cedric Derick Jiatsa Mbouna, Marius Jaures Tsakem Nangap, Aubin Youbi Kamche, Souleyman Hassan, Jean Claude Tchouankeu, Fabrice Fekam Boyom

Due to the spreading resistance to antimalarial drugs, new therapeutics are urgently needed, preferably with novel modes of action. Extracts from Terminalia ivorensis…

#Malaria #Terminalia ivorensis #Drug efficacy #Plasmodium berghei
p. 30-39
10.62313/ijpbp.2024.194
DOI: https://doi.org/10.62313/ijpbp.2024.194

Phytochemical evaluation and acute oral toxicity of crude methanol extract of Pleurotus tuber-regium (Fr.) Singer in laboratory mice (Mus musculus)

Sarah Princess Edoh, Dahiru Sani, Christian Emeka Mbah, Hindatu Yusuf, Abubakar Nuhu Ishaq, Tabita Gaba Sule, Kalen Ephraim Audu

This research aimed to evaluate the phytochemical components of the crude methanol extract (CME) of Pleurotus tuber-regium and its acute toxicity in mice, Mus musculus.…

#Acute oral toxicity #Methanol #Pleurotus tuber-regium #Phytochemicals
p. 68-72
10.29228/ijpbp.18
DOI: https://doi.org/10.29228/ijpbp.18

Biochemical and histological evaluation of kidney, liver, and hematological indices in normal Wistar rats administered dietary formulations of roasted Sphenotylis stenocarpa seeds (Af-rican yam bean)

Nene Hephzibah Chiaka-Onyemeze, Chinelo Chinenye Nkwocha, Affiong Asuquo Edeke, Emmanuel Chimeh Ezeako

Sphenotylis stenocarpa seeds (African yam bean) represent one of the under-exploited nutrient-rich legumes associated with African folklore and disease-remedy claims…

#Sphenostylis stenocarpa #Nephroprotective #Hepatoprotective #Antioxidant
p. 16-24
10.62313/ijpbp.2025.250
DOI: https://doi.org/10.62313/ijpbp.2025.250
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