Biological activities and DNA interactions of aqueous extract of Phlomis linearis (Boiss. & Bal.)

Betül Aydın, Lütfiye Yasemin Gönder, Nebahat Aytuna Çerçi, Yiğit Can Ateş, İlayda Sezin Yalçınkaya, Nüveyre Canbolat, Leyla Açık, Nurcan Karacan, Emine Akyüz Turumtay, Halbay Turumtay

Phlomis linearis Boiss. & Bal. of the Lamiaceae family is one of the endemic species in Turkey, i.e., growing in the east, central, and southeast parts…

#Phlomis linearis #Biological activity #Cytotoxicity #DNA interaction

p. 73-85

10.29228/ijpbp.19

DOI: https://doi.org/10.29228/ijpbp.19

Potentilla fulgens Wall ex Sims. exerts anti-diabetic effects by inhibiting α-amylase and α-glucosidase: deeper insights through molecular docking

Anita Kumari Rai, Careen Liza Pakyntein, Stability Nongrum, Daiahun Thabah, Shelareen Ediemi Sunn, Donkupar Syiem

Potentilla fulgens Wall ex Sims., a local medicinal plant used by the Khasi tribe of Meghalaya, India, has been reported to be rich in tannins, polyphenols,…

#α-Amylase #α-Glucosidase #Diabetes #Docking

p. 1-15

10.62313/ijpbp.2025.244

DOI: https://doi.org/10.62313/ijpbp.2025.244

Comparative toxicity of cinnamon oil, cinnamaldehyde and their nano-emulsions against Culex pipiens (L.) larvae with biochemical and docking studies

Nehad E.M. Taktak, Mohamed E.I. Badawy, Osama M. Awad, Nadia E. Abou El-Ela

The larvicidal activity of cinnamon oil and its main component, cinnamaldehyde, was compared with their nano-emulsions (NEs) against Culex pipiens mosquito larvae.…

#Culex pipiens #Cinnamon oil #Cinnamaldehyde #Nano-emulsions

p. 51-63

10.62313/ijpbp.2022.16

DOI: https://doi.org/10.62313/ijpbp.2022.16

Chemical composition and cholinesterase, tyrosinase, alpha-amylase and alpha-glucosidase inhibitory activity of the essential oil of Salvia tomentosa

Mustafa Kocer, Erman Salih Istıfli

The aim of this study was to determine the chemical composition of Salvia tomentosa (Miller) essential oil and to examine its inhibitory effect on…

#Salvia tomentosa #Essential oil #Enzyme inhibitory activity #Molecular docking

p. 1-16

10.62313/ijpbp.2022.8

DOI: https://doi.org/10.62313/ijpbp.2022.8

Assessment of apigenin-7-glucoside and luteolin-7-glucoside as multi-targeted agents against Alzheimer's disease: a molecular docking study

Erman Salih Istifli, Cengiz Sarikurkcu

Although the incidence of Alzheimer's disease (AD) is increasing in society, unfortunately, no definite progress has been made in treating this disease yet. In this…

#Alzheimer’s disease #AChE #BChE #Amyloid precursor protein

p. 56-64

10.62313/ijpbp.2021.7

DOI: https://doi.org/10.62313/ijpbp.2021.7

Docking-based virtual screening, ADMET, and network pharmacology prediction of anthocyanidins against human alpha-amylase and alpha-glucosidase enzymes as potential antidiabetic agents

Cihan Demir, Erman Salih Istifli

Diabetes mellitus (DM) characterized by high blood sugar concentration is a major global public health problem and untreated DM results in blindness, kidney failure,…

#Structure-based drug design (SBDD) #Anthocyanidin #Drug-likeness #ADMET

p. 271-283

10.29228/ijpbp.9

DOI: https://doi.org/10.29228/ijpbp.9

Natural phenolic compounds from Satureja L. as inhibitors of COVID-19 protease (Mpro): Computational investigations

Faika Başoğlu-Ünal, Selin Tufan, Nur Tan

Coronavirus (SARS-CoV-2) causes a new type of severe acute respiratory syndrome that first appeared in Wuhan in December 2019; it is a very fast-spreading and deadly…

#Satureja L. #Phenolic compounds #COVID-19 #Protease inhibitor (Mpro)

p. 111-117

10.62313/ijpbp.2022.21

DOI: https://doi.org/10.62313/ijpbp.2022.21