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Found 8 items.

"Toxicity"

Toxicity study and ameliorative effects of the aqueous leaf extract of Lecanoidiscus cupanioides Planch (ex. Benth) on the stress-induced ulcer

Ebere Ifejirika Ezeonyi, Earnest Oghenesuvwe Erhirhie, Felix Ahamefule Onyegbule

Lecaniodiscus cupanioides Planch (ex. Benth) is effective in treating burns, fevers, and inflammatory conditions. This study investigates the toxicity effects of the…

#Lecaniodiscus cupanioides #Toxicity studies #Stress induced ulcer #Water immersion
p. 47-55
10.62313/ijpbp.2024.159
DOI: https://doi.org/10.62313/ijpbp.2024.159

Phytochemical evaluation and acute oral toxicity of crude methanol extract of Pleurotus tuber-regium (Fr.) Singer in laboratory mice (Mus musculus)

Sarah Princess Edoh, Dahiru Sani, Christian Emeka Mbah, Hindatu Yusuf, Abubakar Nuhu Ishaq, Tabita Gaba Sule, Kalen Ephraim Audu

This research aimed to evaluate the phytochemical components of the crude methanol extract (CME) of Pleurotus tuber-regium and its acute toxicity in mice, Mus musculus.…

#Acute oral toxicity #Methanol #Pleurotus tuber-regium #Phytochemicals
p. 68-72
10.29228/ijpbp.18
DOI: https://doi.org/10.29228/ijpbp.18

Pergularia daemia (Apocynaceae) mitigates rifampicin-induced hepato-renal injury: potentials in the management of liver and kidney diseases

Temidayo Ogunmoyole, Omotola Grace Fatile, Olaitan Daniel Johnson, Adewale Akeem Yusuff

Medicinal potentials of Pergularia daemia leaves in managing hepato-renal toxicity induced by rifampicin were investigated. Twenty-five (25) Wistar rats were randomly…

#Pergularia daemia #Liver #Kidney #Biomarkers
p. 196-204
10.62313/ijpbp.2022.38
DOI: https://doi.org/10.62313/ijpbp.2022.38

Traditional uses, phytochemistry, and toxic potential of Teucrium polium L.: A comprehensive review

Arzuhan Sihoglu Tepe, Mehmet Ozaslan, Ibrahim Halil Kilic, Sibel Bayil Oguzkan

The aim of this study was to present information about the traditional use and phytochemistry of T. polium, to discuss contradictory views about chemotaxonomy and its…

#Teucrium polium #Ethnopharmacology #Phytochemistry #Toxicity
p. 1-41
10.62313/ijpbp.2021.1
DOI: https://doi.org/10.62313/ijpbp.2021.1

Variation in chemical composition, insecticidal and antioxidant activities of essential oils from the leaves, stem barks, and roots of Blighia unijugata (Baker) and B. sapida (K. D. Koenig)

Ganiyat K. Oloyede, Patricia A. Onocha, ThankGod R. Ikiroma, Olusegun W. Olusola

Blighia unijugata (Baker) and B. sapida (K.D. Koenig) (Sapindaceae) are forest trees widespread in Tropical Africa. They are used in folk medicine for the treatment of…

#Blighia unijugata #Blighia sapida #Sitophillus zeamaise #Essential oil
p. 10-17
10.29228/ijpbp.11
DOI: https://doi.org/10.29228/ijpbp.11

Cytotoxic and apoptotic effects of Prunus spinosa fruit extract on HT-29 colon cancer line

Fulya Dilek Gökalp, Egzona Qipa

Colon cancer holds the position of the third most common type of cancer and stands as the third leading cause of cancer-related deaths for both men and women. Modern…

#Prunus spinosa #Ethidium bromide/Acridine Orange #MTT #Apoptosis
p. 64-70
10.62313/ijpbp.2024.161
DOI: https://doi.org/10.62313/ijpbp.2024.161

Comparative toxicity of cinnamon oil, cinnamaldehyde and their nano-emulsions against Culex pipiens (L.) larvae with biochemical and docking studies

Nehad E.M. Taktak, Mohamed E.I. Badawy, Osama M. Awad, Nadia E. Abou El-Ela

The larvicidal activity of cinnamon oil and its main component, cinnamaldehyde, was compared with their nano-emulsions (NEs) against Culex pipiens mosquito larvae.…

#Culex pipiens #Cinnamon oil #Cinnamaldehyde #Nano-emulsions
p. 51-63
10.62313/ijpbp.2022.16
DOI: https://doi.org/10.62313/ijpbp.2022.16

Ameliorative effect of zingerone on cadmium-induced nephrotoxicity in adult wistar rats

Augustine Oviosun, Emeka Godson Anyanwu, Ezinne Chidinma Oviosun, Okwara Blasius Okechukwu

Exposure to heavy metals like cadmium has been reported to cause severe kidney damage through oxidative stress and inflammation. Zingerone is a bioactive compound…

#Zingerone #Oxidative stress #Renal toxicity #Cadmium
p. 118-124
10.62313/ijpbp.2024.238
DOI: https://doi.org/10.62313/ijpbp.2024.238
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