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Ameliorative effect of zingerone on cadmium-induced nephrotoxicity in adult wistar rats

Augustine Oviosun, Emeka Godson Anyanwu, Ezinne Chidinma Oviosun, Okwara Blasius Okechukwu

Exposure to heavy metals like cadmium has been reported to cause severe kidney damage through oxidative stress and inflammation. Zingerone is a bioactive compound…

#Zingerone #Oxidative stress #Renal toxicity #Cadmium

p. 118-124

10.62313/ijpbp.2024.238

DOI: https://doi.org/10.62313/ijpbp.2024.238

Vernonia amygdalina leaf extract protects against carbon tetrachloride-induced hepatotoxicity and nephrotoxicity: a possible potential in the management of liver and kidney diseases

Temidayo Ogunmoyole, Yetunde Beatrice Apanisile, Yusuff Adewale Akeem, Omowumi Jayeola Makun

The rising prevalence of liver and kidney diseases is worrisome and constitutes a major threat to public health. The present study investigates the medicinal potentials…

#Vernonia amygdalina #Rat #Kidney #Liver

p. 1-9

10.29228/ijpbp.10

DOI: https://doi.org/10.29228/ijpbp.10

Therapeutic effect of the solvent fraction of hexane leaf extract of Tapinanthus bangwensis (Engl. & K. Krause) (Loranthaceae) in alloxan-induced pathology in diabetic rats

Godwin Okwudiri Ihegboro, Chimaobi James Ononamadu, Mujiburrahman Fadilu, Peter Prince Oghenekome, Bello Jacob, Sunday Edwin

Plant-based products are gradually replacing pharmaceuticals in treating ailments, including diabetes, due to their safety, cost-effectiveness, potency, and…

#Oxidative stress #Tapinanthus bangwensis #Diabetic rats #Haematopoietic markers

p. 79-89

10.62313/ijpbp.2024.196

DOI: https://doi.org/10.62313/ijpbp.2024.196

Toxicity study and ameliorative effects of the aqueous leaf extract of Lecanoidiscus cupanioides Planch (ex. Benth) on the stress-induced ulcer

Ebere Ifejirika Ezeonyi, Earnest Oghenesuvwe Erhirhie, Felix Ahamefule Onyegbule

Lecaniodiscus cupanioides Planch (ex. Benth) is effective in treating burns, fevers, and inflammatory conditions. This study investigates the toxicity effects of the…

#Lecaniodiscus cupanioides #Toxicity studies #Stress induced ulcer #Water immersion

p. 47-55

10.62313/ijpbp.2024.159

DOI: https://doi.org/10.62313/ijpbp.2024.159

Pergularia daemia (Apocynaceae) mitigates rifampicin-induced hepato-renal injury: potentials in the management of liver and kidney diseases

Temidayo Ogunmoyole, Omotola Grace Fatile, Olaitan Daniel Johnson, Adewale Akeem Yusuff

Medicinal potentials of Pergularia daemia leaves in managing hepato-renal toxicity induced by rifampicin were investigated. Twenty-five (25) Wistar rats were randomly…

#Pergularia daemia #Liver #Kidney #Biomarkers

p. 196-204

10.62313/ijpbp.2022.38

DOI: https://doi.org/10.62313/ijpbp.2022.38

Phytochemical evaluation and acute oral toxicity of crude methanol extract of Pleurotus tuber-regium (Fr.) Singer in laboratory mice (Mus musculus)

Sarah Princess Edoh, Dahiru Sani, Christian Emeka Mbah, Hindatu Yusuf, Abubakar Nuhu Ishaq, Tabita Gaba Sule, Kalen Ephraim Audu

This research aimed to evaluate the phytochemical components of the crude methanol extract (CME) of Pleurotus tuber-regium and its acute toxicity in mice, Mus musculus.…

#Acute oral toxicity #Methanol #Pleurotus tuber-regium #Phytochemicals

p. 68-72

10.29228/ijpbp.18

DOI: https://doi.org/10.29228/ijpbp.18

Biochemical and histological evaluation of kidney, liver, and hematological indices in normal Wistar rats administered dietary formulations of roasted Sphenotylis stenocarpa seeds (Af-rican yam bean)

Nene Hephzibah Chiaka-Onyemeze, Chinelo Chinenye Nkwocha, Affiong Asuquo Edeke, Emmanuel Chimeh Ezeako

Sphenotylis stenocarpa seeds (African yam bean) represent one of the under-exploited nutrient-rich legumes associated with African folklore and disease-remedy claims…

#Sphenostylis stenocarpa #Nephroprotective #Hepatoprotective #Antioxidant

p. 16-24

10.62313/ijpbp.2025.250

DOI: https://doi.org/10.62313/ijpbp.2025.250