Exploring the phytochemistry and pharmacology of Mangifera indica L. (Mango) leaves: A review

Humna Mehmood; Jawaria Mehmood; Noor Zulfiqar

doi:10.29228/ijpbp.38

Authors

Humna Mehmood University of Agriculture Faisalabad, Department of Chemistry, Faisalabad, Pakistan https://orcid.org/0009-0009-9552-6542
Jawaria Mehmood University of Agriculture, Fisheries and Wildlife, Department of Zoology, Faisalabad, Pakistan https://orcid.org/0009-0009-2439-233X
Noor Zulfiqar University of Agriculture Faisalabad, Department of Chemistry, Faisalabad, Pakistan https://orcid.org/0009-0004-4171-682X

DOI:

https://doi.org/10.29228/ijpbp.38

Keywords:

Mangifera indica, Phytochemistry, Pharmacological activities, Anticancer, Antidiabetic

Abstract

Mangifera indica L. (Mango), a member of the Anacardiaceae family, is native to the tropical and subtropical regions of the world. Leaves of M. indica exhibit pharmacological potential as a panacea. The current study aimed to systematically review the phytochemistry and biological effects of M. indica leaves (MILs). Google Scholar, PubMed, Scopus, and Web of Science were used to review the relevant literature. MILs are reported to possess remarkable medicinal properties owing to a plethora of phytochemicals, namely, minerals, vitamins, flavonoids, phenolic acids, terpenes, benzophenones, tannins, saponins, and alkaloids. MILs have been investigated for numerous therapeutic effects, including anticancer, anti-diabetic, antioxidant, antiviral, antibacterial, antifungal, antidiarrheal, antiulcer, gastrointestinal, anti-obesity, cardio-protection, hypotensive, analgesic, and hepato-protection. In this review, phytochemistry, pharmacology as well as toxicology of MILs have been critically discussed. Considering their phytochemical profile and pharmacological benefits, MILs can be used for the development of valuable pharmaceutical products. However, more comprehensive clinical trials are needed to be conducted for further evaluation of its effectiveness.

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